Host Metabolic Response in Early Lyme Disease
نویسندگان
چکیده
منابع مشابه
Early and specific antibody response to OspA in Lyme Disease.
Borrelia burgdorferi (Bb), the cause of Lyme disease, has appeared not to evoke a detectable specific antibody response in humans until long after infection. This delayed response has been a biologic puzzle and has hampered early diagnosis. Antibody to the abundant organism-specific outer surface proteins, such as the 31-kD OspA, has rarely been detected less than 6 mo after infection. Antibody...
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A 22-year-old woman was admitted to the hospital with fevers, neck pain, the “worst headache of her life,” and bilateral knee pain. The patient reported a history of uveitis and recounted a recent tick exposure. Physical examination revealed multiple red, circular, nonpruritic skin lesions with bull’s-eye appearances that were approximately 2 inches in diameter and located on the patient’s legs...
متن کاملThe antibody response in Lyme disease.
We determined the antibody response against the Ixodes dammini spirochete in Lyme disease patients by indirect immunofluorescence and an enzyme-linked immunosorbent assay (ELISA). The specific IgM response became maximal three to six weeks after disease onset, and then declined, although titers sometimes remained elevated during later disease. Specific IgM levels correlated directly with total ...
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I n the mid-1970s, several children in the town of Lyme, Connecticut, began to suffer from painful, swollen joints. They were diagnosed with juvenile rheumatoid arthritis, a rare condition. Clinicians at Yale School of Medicine suspected the cluster of cases was caused by an infectious agent. 1 The illness, dubbed Lyme disease, was soon recorded in an increasing number of patients in the northe...
متن کاملReport of a case of Lyme disease in Mazandaran
Lyme disease is caused by the spirochete Borrelia burgdorferi. Depending on the stage of illness, infection may be limited to the skin or involve the cardiac, nervous and musculoskeletal systems. Herein, we report a case of Lyme disease in a 23-year-old woman from North of Iran (Mazandaran) in early-localized stage of erythema chronicum migrans. The diagnosis was confirmed by the presence of se...
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ژورنال
عنوان ژورنال: Journal of Proteome Research
سال: 2019
ISSN: 1535-3893,1535-3907
DOI: 10.1021/acs.jproteome.9b00470